| Interstate | Exit(mm) | Dir | Locale | Type |
| 20 | (93) | wb | Lugoff | Rest Area |
| 20 | (93) | eb | Lugoff | Rest Area |
| 20 | (0.5) | eb | North Augusta | Welcome Center |
| 26 | (204) | eb | Ladson | Rest Area |
| 26 | (152) | wb | Orangeburg | Rest Area |
| 26 | (150) | eb | Orangeburg | Rest Area |
| 26 | (123) | wb | Gaston | Rest Area |
| 26 | (123) | eb | Gaston | Rest Area |
| 26 | (63) | wb | Kinards | Rest Area |
| 26 | (63) | eb | Kinards | Rest Area |
| 26 | (9) | wb | Inman | Turnout |
| 26 | (9) | eb | Inman | Turnout |
| 26 | (3) | eb | Landrum | Welcome Center |
| 77 | (89) | sb | Fort Mill | Welcome Center |
| 77 | (65) | sb | Richburg | Rest Area |
| 77 | (65) | nb | Richburg | Rest Area |
| 85 | (103) | sb | Blacksburg | Welcome Center |
| 85 | (88) | sb | Gaffney | Rest Area |
| 85 | (24) | sb | Anderson | Rest Area |
| 85 | (17) | nb | Anderson | Rest Area |
| 85 | (0.5) | nb | Fair Play | Welcome Center |
| 95 | (195) | sb | Dillon | Welcome Center |
| 95 | (171) | sb | Florence | Rest Area |
| 95 | (171) | nb | Florence | Rest Area |
| 95 | (139) | sb | Shiloh | Rest Area |
| 95 | (139) | nb | Shiloh | Rest Area |
| 95 | (99) | sb | Santee | Welcome Center |
| 95 | (99) | nb | Santee | Rest Area |
| 95 | (47) | sb | Walterboro | Rest Area |
| 95 | (47) | nb | Walterboro | Rest Area |
| 95 | (4) | nb | Hardeeville | Welcome Center |
| 385 | (5) | sb | Laurens | Rest Area |
| 385 | (5) | nb | Laurens | Rest Area |
South Carolina
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